Interventions for Tuberculosis Control and Elimination
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As we are going to discuss interventions, we must keep in mind the difference between efficacy, effectiveness, and efficiciency. Efficacy must be established first, but the setting of efficacy testing often has experimental character and is carried out under as much as possibly controlled conditions. Whether an efficacious intervention is also effective under routine program conditions must be evaluated separately. As an example, a vaccine might be highely efficacious but if it depends on a functional cold chain which is defunct in a given country, it cannot be effective, and using it would also be very inefficient under such cirumstances.
