Interventions for Tuberculosis Control and Elimination
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Isoniazid was the first anti-tuberculosis drug ever developed. It was synthesized at the German University of Prague by two chemists without the recognition of its anti-tuberculosis properties.
The high efficacy of isoniazid was recognized only in 1952 when three pharmaceutical companies independently again synthesized the compound. Because the patent had expired, it turned out that the most efficacious antituberculosis drug could be generically and inexpensively produced right from the beginning of its introduction to chemotherapy.
