Slide 061 Interventions for Tuberculosis Control and Elimination
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Mutants resistant to drug A will be killed by drug B. However, if drug A is given and taken in sub-inhibitory concentrations, there will be some suppression of growth of bacilli susceptible to drug A but none of bacilli resistant to drug A. At the end of the cycle, mutants resistant to drug A will have gained an advantage.
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Last update: September 29, 2010