Interventions for Tuberculosis Control and Elimination
Next
Previous
First
Last
The early bactericidal activity varies for different drugs. Among the essential drugs, isoniazid is the one with the highest early bactericidal activity. Isoniazid-susceptible bacilli are thus killed more rapidly than isoniazid-resistant bacilli. If treatment is stopped after this initial killing, isoniazid-resistant mutants have thus an advantage during regrowth.
